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Methylation and methyl donor status NNMT consumes methyl donors as part of its enzymatic function

10.1016/j.ejphar.2016.05.033 127 TorranceN.FergusonJ

The authors also noted that intramuscular and oral tocopherol administration had a similar effect

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These were isolated from patients with various disease symptoms, as well as from a 5300-year-old European natural mummy, named Iceman (Maixner et al